The Effects of Antibiotic Syrups on the Color Stability and Surface Roughness of Various Restorative Materials Used in Pediatric Dentistry

Background: This study aimed to evaluate the effects of commonly prescribed pediatric antibiotic syrups on the color stability and surface roughness of restorative materials used in pediatric dentistry.

Methods: Disc-shaped specimens (5 × 2 mm) were prepared from composite resin (G-ænial), compomer (Dyract XP), and glass ionomer cement (Equia Forte Fil). Initial color measurements were recorded using a spectrophotometer at 3 different points, with each measurement repeated 3 times. Surface roughness (Ra) values were obtained from 3 distinct angles under standardized conditions. The specimens were divided into 2 subgroups (n = 5) and immersed in Klamoks 400 mg suspension and Macrol 250 mg suspension for 2 minutes every 12 hours over 1 week. A control group was maintained in distilled water. Color change (ΔE) and surface roughness measurements were reassessed at the end of the experimental period. Statistical analyses were performed using IBM SPSS 22 (P < .05).

Results: The highest color change (ΔE: 5.35 ± 0.97) was observed in the Klamoks-composite group, while the lowest was in the Macrol-compomer group (ΔE: 0.38 ± 0.12). Surface roughness increased most significantly in Klamoks-GIC (0.91 ± 0.20), while Klamoks-composite exhibited the lowest Ra values (0.51 ± 0.19) (P < .05).

Conclusion: Pediatric antibiotic syrups significantly impact the color stability and surface roughness of restorative materials due to their low pH, high viscosity, and prolonged exposure. These findings suggest that material selection in pediatric restorative treatments should consider potential interactions with pediatric medications to enhance restoration longevity.